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A booster dose of vaccines is recommended for persons over 18 years of age who have received two doses of vaccines more than 6 months ago. The optimal revaccination period is 6 to 9 months after completion of the initial vaccination course, regardless of the vaccine used.

The booster dose restores the potency of COVID-19 vaccines, the efficacy of which, according to the latest global data, is gradually declining over time. In addition, the booster dose should provide additional protection, given the emergence of new mutated strains such as Omicron.

Studies show that booster doses of mRNA vaccines show the best results after vaccination with two doses of other vaccine types. For the booster dose, Pfizer-BioNTech's Moderna or Comirnaty mRNA vaccines are preferred, regardless of which vaccine the person was vaccinated with. For those who have received the first two vaccines with Sinovac Biotech's CoronaVac, a booster dose with Pfizer's vaccine is recommended.